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BBC Sport examines some of the key themes before Sunday's match (14:00 BST), with Liverpool boss Andoni Iraola returning to former club Bournemouth. Bournemouth's 2-2 draw with Brentford followed a frustratingly familiar pattern for head coach Marco Rose, who remains without a Premier League win.
The Red Devils, who were dumped out of the Carabao Cup by Brighton on Wednesday, have won just one of their opening four Premier League games this season to leave them 13th, already eight points adrift of the early pace-setters Arsenal and Manchester City. The Brighton defeat rounded off a difficult few days for United head coach Michael Carrick, whose side were insipid in the Manchester derby loss to 10-man City last Sunday. Throw in the uncertainty over academy star JJ Gabriel's future and Carrick is in dire need of three points on the road in west London.
Manchester City will look to maintain their 100% league record under Enzo Maresca when they welcome Sunderland to Etihad Stadium on Sunday. Maresca's tenure got off to a wobbly start with the Community Shield defeat by Arsenal, but his troops have rallied to ensure they are level on points with the table-topping Gunners at this early stage, trailing only on goal difference. In fact, the Italian is aiming to become just the sixth manager to win his first five Premier League games in charge of a club.
In-form Leeds United test their unbeaten record against a Crystal Palace side who have problems in defence. BBC Sport takes a look at the key themes going into Sunday's game at Elland Road. Up to third in the league and boasting a record of just one defeat in 13 league matches – and just five in their past 29 - these are great times for Leeds fans.
