New microscopy method achieves angstrom-scale localization precision with one laser‎

Researchers in the lab of Sam Peng, the Pfizer Inc.–Gerald Laubach Career Development Assistant Professor of Chemistry at MIT and a core institute member of the Broad Institute of MIT and Harvard, have developed a super-resolution imaging technology. It allows scientists to visualize molecular structures with angstrom-level localization precision—three orders of magnitude beyond the nanometer-scale limits of standard fluorescent dyes—while simplifying the imaging process.