Synchrotron X-rays uncover hidden protein binding sites, enabling two new functions‎

Using bright X-rays from the Department of Energy's SLAC National Accelerator Laboratory and Lawrence Berkeley National Laboratory (Berkeley Lab), researchers pioneered an innovative approach to designing proteins with targeted functions. Their method generated new insights that allowed the team to turn a single designed protein into two new proteins with completely different functions—one of which is the most active designed enzyme to date.