Understanding how cells take up and use isolated mitochondria to restore energy function‎

Mitochondria are essential for cell survival, repair, and adaptation. Not only do they generate most of the energy needed during a cell's life, but they also regulate cell death, calcium balance, and responses to stress. When mitochondria fail, which is a common feature of neurodegenerative diseases and many inflammatory and metabolic disorders, cells lose their ability to meet energy demands and maintain internal stability.