תפריט כתבה
Immunoglobulin G's overlooked hinge turns out to be a structural control hub
Phys
21:11
The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single amino acid in this region transforms a full-length antibody into a stable half-IgG1 molecule with altered immune activity.